Home > Uncategorized > Diagnostic performance z-score of cardiac Troponin in patients with suspected acute coronary syndrome

Diagnostic performance z-score of cardiac Troponin in patients with suspected acute coronary syndrome

This paper is instructive of an emerging approach to interpretation of low level troponin in patients presenting with acute coronary syndrome.

The following comments of Dr William Parsonage provide guiding insights:

A. Patients with a z-score of >2 that WERE NOT diagnosed with Type 1 AMI – as you can see the majority of these (and essentially all of those with z>3) had significant other cardiac diagnosis and probably would fit the diagnosis of type 2 AMI, and

B. Those with z-score of <2 that WERE diagnosed with Type 1 AMI – again, there were not many of these and in most cases the absolute troponin levels were significantly elevated and one would doubt whther the z-score would really come into play.

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