Home > Uncategorized > Angiopoietin-like 4 (ANGPTL4): a new target

Angiopoietin-like 4 (ANGPTL4): a new target

Genotype-phenotype correlation studies of inactivating mutations of ANGPTL4 are presented in the New Engl J Med.  These mutations appear to lower triglycride (+ modest elevation HDL) and have lower odds ratio for coronary artery disease.

 

From “Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease”

 

aangpl402

 

 

angptl405

angptl03

From “Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease”.

angptl401

 

The editorial is available here.

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