Home > Uncategorized > Cochrane Review: Colchicine in Cardiovascular Disease: Efficacy and Safety

Cochrane Review: Colchicine in Cardiovascular Disease: Efficacy and Safety

A Cochrane review of the use of colchicine in cardiovascular disease performed a meta-analysis of randomized clinical trials (with placebo control)  of at least 6 month duration. The efficacy studies were of moderate quality. A clinically important effect size may be present. However, the uncertainty of benefits may not outweigh adverse effects (see forest plot). The safety end-points data was low quality. There was also no evidence to support use of colchicine dose > 1 mg/day.

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