Posts Tagged ‘chocolate’

Chocolate Consumption and Apparent Atrial Fibrillation

Mostofsky et al (Heart Online First, published on May 23, 2017 as 10.1136/heartjnl-2016-310357) report a large population cohort study and assess the relationship between chocolate consumption and risk of apparent atrial fibrillation.



To evaluate the association between chocolate intake and incident clinically apparent atrial fibrillation or flutter (AF).


The Danish Diet, Cancer, and Health Study is a large population-based prospective cohort study. The present study is based on 55 502 participants (26 400 en and 29 102 women) aged 50–64 years who had provided information on chocolate intake at baseline.
Incident cases of AF were ascertained by linkage with nationwide registries.


During a median of 13.5 years there were 3346 cases of AF. Compared with chocolate intake less than once per month, the rate of AF was lower for people consuming 1–3 servings/month (hazard ratio (HR) 0.90, 95% confidence interval (CI) 0.82 to 0.98), 1
serving/week (HR 0.83, 95% CI 0.74 to 0.92), 2–6 servings/week (HR 0.80, 95% CI 0.71 to 0.91) and ≥1 servings/day (HR 0.84, 95% CI 0.65 to 1.09; p-linear trend <0.0001), with similar results for men and women.


Accumulating evidence indicates that moderate chocolate intake may be inversely associated with AF risk, although residual confounding cannot be ruled out.